ESPE Yearbook of Paediatric Endocrinology

ESPE Yearbook of Paediatric Endocrinology

ISSN 1662-4009 (online)

Published by BioScientifica

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ey0016.4-14 | Mechanism of the Year | ESPEYB16

4.14. IGF-2 preprograms maturing macrophages to acquire oxidative phosphorylation-dependent anti-inflammatory properties

L Du , L Lin , Q Li , K Liu , Y Huang , X Wang , K Cao , X Chen , W Cao , F Li , C Shao , Y Wang , Y Shi

To read the full abstract: Cell Metab. 2019 4;29:1363–1375.Mesenchymal stem and/or stromal cells (MSCs) regulate immune system and have been associated with inflammatory and autoimmune diseases. The IGF system is mainly known for its role in the regulation of growth, development and metabolism. A possible role of IGF-I in inflammation has recently been proposed [1, 2], whereas the e...
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ESPE Yearbook of Paediatric Endocrinology
ISSN 1662-4009 (Online)
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